Prof. Dr. med. Arnd Schaefer

Fachgebiet

Interventionelle Kardiologie, Klappentherapie, ASD- und PFO-Verschlüsse

 

Der außerplanmäßige Professor der MHH ist ein herausragender Experte der interventionellen Kardiologie und Echokardiographie in Deutschland. Er war langjähriger Leiter des Herzkatheterlabors der MHH.

 

Lebenslauf

  • 1990 – 1996 Studium der Humanmedizin an der Philips-Universität Marburg
  • 1996 Wissenschaftlicher Mitarbeiter an der Medizinischen Hochschule Hannover, 
    Klinik für Kardiologie und Angiologie (Direktor: Professor Dr. med. H. Drexler)
  • 2002 Facharzt für Innere Medizin
  • 2004 Zusatzbezeichnung Kardiologie
  • 2005 Leiter des Echokardiographie-Labors der Klinik für Kardiologie und Angiologie der Medizinischen Hochschule Hannover
  • 2006 Aufbau und Leiter Chest Pain Unit der MHH
  • 2006 Habilitation
  • 2009 Verantwortlicher Oberarzt der kardiologischen Intensivstation
  • 2009 Ernennung zum Leitenden Oberarzt der Klinik für Kardiologie und Angiologie
  • 2009 Verantwortlicher Oberarzt Herzkatheterlabor
  • 2010 Zertifizierung interventioneller Aortenklappenersatz
  • 2010 Einführung interventionelle Mitralklappenrekonstruktion an der MHH
  • 2010 Zusatzbezeichung internistische Intensivmedizin
  • 2011 Ernennung zum Außerplanmäßigen Professor an der Medizinischen Hochschule Hannover
  • 2012 Geschäftsführender Partner der Gemeinschaftspraxis HERZ IM ZENTRUM HANNOVER
  • 2014 Zertifizierung "interventionelle Kardiologie" durch die Deutsche Gesellschaft für Kardiologie

 

 

Zusätzliche Aufgaben / Mitgliedschaften

  • Berufsverband Deutscher Internisten (BDI)
  • American Society of Echocardiography (ASE)
  • Deutsche Gesellschaft für Kardiologie (DGK)

 

 

Schwerpunkte

Diagnostik und Therapie von Herzklappenfehlern (interventioneller Aorten- und Mitralklappenersatz), ASD- und PFO-Verschlüsse und Echokardiographie, PTCA und Stentimplantation.

Publikationen der letzten Jahre

Klein G, Schröder F, Vogler D, Schaefer A, Haverich A, Schieffer B, Korte T,
Drexler H
Increased open probability of single cardiac L-type calcium channels in patients with chronic atrial fibrillation. role of phosphatase 2A.
Cardiovasc Research 2003 Jul 1; 59 (1):37-45

Schaefer A, Klein G, Brand B, Lippolt P, Drexler H, Meyer GP
Evaluation of left ventricular diastolic function by pulsed Doppler tissue imaging in mice.
Journal of the American Society of Echocardiography 2003 Nov; 16(11):1144-9.

Hilfiker-Kleiner D, Hilfiker A, Fuchs M, Kaminski K, Schaefer A, Schieffer B, Hillmer A, Schmiedl A, Ding Z, Podewski E, Podewski E, Poli V, Schneider MD, Schulz R, Park JK, Wollert KC, Drexler H
Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury.
Circulation Research. 2004 Jul 23; 95(2):187-95

Schaefer A, Meyer GP, Waldow A, Weiss T, Hausmann D, Drexler H
Images in cardiovascular medicine: Pulmonary valve endocarditis.
Circulation 2001 Mar 6;103(9):E53-4

Meyer GP, Laudenberg B, Hausmann D, Mugge A, Cremer J, Hornig B, Weiss T, Hecker H, Haverich A, Drexler H, Schaefer A
Transthoracic Doppler validation in mammary artery grafts after minimal invasive direct coronary artery bypass operation.
Journal of the American Society of Echocardiography. 2004 Sep;17 (9):954-61.

Engberding N, Spiekermann S, Schaefer A, Heineke A, Wiencke A, Muller M, Fuchs M, Hilfiker-Kleiner D, Hornig B, Drexler H, Landmesser U. Related Articles, Links
Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug?
Circulation 2004 Oct 12; 110 (15):2175-9.

Landmesser U, Engberding N, Bahlmann FH, Schaefer A, Wiencke A, Heineke A, Spiekermann S, Hilfiker-Kleiner D, Templin C, Kotlarz D, Mueller M, Fuchs M, Hornig B, Haller H, Drexler H
Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase.
Circulation 2004 Oct 5; 110 (14):1933-9

Schaefer A, Klein G, Fischer D, Meyer GP, Drexler H, Hausmann D.
Mechanism of coronary artery restenosis after stenting for acute myocardial infarction.
American Journal of Cardiology 2004 Oct 15; 94 (8):1037-40

Heineke J, Ruetten H, Willenbockel C, Gross SC, Naguib M, Schaefer A, Kempf T, Hilfiker-Kleiner D, Caroni P, Kraft T, Kaiser RA, Molkentin JD, Drexler H, Wollert KC. Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.
Proceedings of the National Academy of Sciences 2005 Feb 1;102 (5):1655-60.

Klein G, Schaefer A, Hilfiker-Kleiner D, Oppermann D, Shukla P, Quint A, Podewski E, Hilfiker A, Schroder F, Leitges M, Drexler H
Increased collagen deposition and diastolic dysfunction but preserved myocardial hypertrophy after pressure overload in mice lacking PKCepsilon.
Circulation Research 2005 Apr 15; 96 (7):748-55

Schaefer A, Meyer GP, Brand B, Hilfiker-Kleiner D, Drexler H, Klein G
Effects of anesthesia on diastolic function in mice assessed by echocardiography
Echocardiography 2005

Hilfiker-Kleiner D, Hilfiker A, Kaminski K, Schaefer A, Park J, Michel K, Quint A, Yaniv M, Weitzmann JB, Drexler H
The lack of Jund D promotes pressure overload induced apoptosis, hypertrophic growth and angiogenesis in the heart
Circulation 2005 in

Schaefer A, Meyer GP, Hilfiker-Kleiner D, Brand B, Drexler H, Klein G
Evaluation of Tissue Doppler Tei index for global left ventricular function in mice after myocardial infarction: comparison with Pulsed Doppler Tei index
European Journal of Echocardiography 2005

Schaefer A, Meyer GP, Fuchs M, Klein G, Kaplan M, Wollert KC, Drexler H
Intracoronary bone marrow cell transfer prevents the progression of diastolic dysfunction in patients after acute myocardial infarction: Results from the BOOST trial
European Heart Journal

Limbourg F, Ringes-Lichtenberg S, Schaefer A, Jacoby C, Mehraein Y, Jäger M, Fuchs M, Klein G, LImbourg A, Ballmaier M, Schlitt HJ, Schrader J, Hilfiker-Kleiner D, Drexler H
Haematopoietic stem cells rescue cardiac function after infarction without permanent cardiac engraftment
European Journal of Heart Failure 2005; 722-729

Sorrentino S, Doerries C, Manes C, Speer D, Lobysheva I, Mohmand W, Akbar R, Bahlmann F Besler C; Schaefer A, Hilfiker-Kleiner D, Lüscher TF; Balligand J, Drexler H, Landmesser U
Nebivolol Exerts Beneficial Effects on Endothelial Function, Early Endothelial Progenitor Cells, Myocardial Neovascularisation, and Left Ventricular Dysfunction Early After Myocardial Infarction Beyond Conventional β1-Blockade
Journal of the American College of Cardiology; 2010

Fischer D, Haentjes J, Klein G, Schieffer B, Drexler H, Meyer GP, Schaefer A
Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism. Procedural and follow-up results after implantation of the Amplatzer®-occluder device
Journal of Interventional Cardiology 2010

Schaefer A, Tallone EM, Westhoff-Bleck M, Klein G, Drexler H, Röntgen P
Relation of diastolic and systolic function, exercise capacity and brain natriuretic peptide in adults after Mustard procedure for transposition of the great arteries
Cardiology 2010

Schaefer A, Rathmann A, Klein G, Drexler H, Tallone EM
Diagnostic accuracy of handheld echocardiography for evaluation of aortic stenosis.
Echocardiography. 2010 May;27(5):481-6.

Hilfiker-Kleiner D, Shukla P, Klein G, Schaefer A, Stapel B, Hoch M, Müller W, Scherr M, Theilmeier G, Ernst M, Hilfiker A, Drexler H.
Continuous glycoprotein-130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction.
Circulation. 2010 Jul 13;122(2):145-55.

Schaefer A, Zwadlo C, Fuchs M, Meyer GP, Lippolt P, Wollert KC, Drexler H.
Long-term effects of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: 5-year results from the randomized-controlled BOOST trial -an echocardiographic study-.
European Journal of Echocardiography 2010 Mar;11(2):165-71.

Meyer GP, Wollert KC, Lotz J, Pirr J, Rager U, Lippolt P, Hahn A, Fichtner S, Schaefer A, Arseniev L, Ganser A, Drexler H.
Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial.
European Heart Journal 2009 Dec;30(24):2978-84.

Fischer D, Fuchs M, Schaefer A, Schieffer B, Jategaonkar S, Hornig B, Drexler H, Meyer GP.
Transcatheter closure of patent foramen ovale in patients with paradoxical embolism. Procedural and follow-up results after implantation of the Starflex occluder device with conjunctive intensified anticoagulation regimen.
Journal of Interventional Cardiology. 2008 Apr;21(2):183-9.

Doerries C, Grote K, Hilfiker-Kleiner D, Luchtefeld M, Schaefer A, Holland SM, Sorrentino S, Manes C, Schieffer B, Drexler H, Landmesser U.
Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.
Circulation Research 2007 Mar 30;100(6):894-903.

Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, Forster O, Quint A, Landmesser U, Doerries C, Luchtefeld M, Poli V, Schneider MD, Balligand JL, Desjardins F, Ansari A, Struman I, Nguyen NQ, Zschemisch NH, Klein G, Heusch G, Schulz R, Hilfiker A, Drexler H.
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy.
Cell. 2007 Feb 9;128(3):589-600.

Grote K, Ortmann M, Salguero G, Doerries C, Landmesser U, Luchtefeld M, Brandes RP, Gwinner W, Tschernig T, Brabant EG, Klos A, Schaefer A, Drexler H, Schieffer B.
Critical role for p47phox in renin-angiotensin system activation and blood pressure regulation.
Cardiovascular Research 2006 Aug 1;71(3):596-605.

Meyer GP, Wollert KC, Lotz J, Steffens J, Lippolt P, Fichtner S, Hecker H, Schaefer A, Arseniev L, Hertenstein B, Ganser A, Drexler H.
Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial.
Circulation. 2006 Mar 14;113(10):1287-94.

Templin C, Kotlarz D, Marquart F, Faulhaber J, Brendecke V, Schaefer A, Tsikas D, Bonda T, Hilfiker-Kleiner D, Ohl L, Naim HY, Foerster R, Drexler H, Limbourg FP.
Transcoronary delivery of bone marrow cells to the infarcted murine myocardium: feasibility, cellular kinetics, and improvement in cardiac function.
Basic Res Cardiol. 2006 Jul;101(4):301-10

Divchev D, Podewski EK, Mengel M, Meyer GP, Drexler H, Schaefer A.
Inflammatory, abscess-forming foreign body reaction mimics a thrombus formation on an atrial septal defect closure device: A commented case report.
Eur J Echocardiogr. 2007 Aug;8(4):298-302.

Templin C, Schaefer A, Stumme B, Drexler H, von Depka M.
Combined aspirin and clopidogrel resistance associated with recurrent coronary stent thrombosis.
Clin Res Cardiol. 2006 Feb;95(2):122-126

Tutarel O, Schaefer A, Fuchs M.
Four decades with the Starr-Edwards ball valve in the aortic position
J Heart Valve Dis. 2009 Jul;18(4):453-454

Fischer D, Haentjes J, Klein G, Schieffer B, Drexler H, Meyer GP, Schaefer A.
Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism: procedural and follow-up results after implantation of the Amplatzer®-occluder device.
J Interv Cardiol. 2011 Feb;24(1):85-91.

Fischer D, Gardiwal A, Haentjes J, Klein G, Meyer GP, Drexler H, Hausmann D, Schaefer A.
Sustained risk of recurrent thromboembolic events in patients with patent foramen ovale and paradoxical embolism: long-term follow-up over more than 15 years.
Clin Res Cardiol. 2012 Apr;101(4):297-303.